This site is intended for US Healthcare Professionals only.
This site is intended for US Healthcare Professionals only.

Current Disease Management Strategies

Today, disease management for fibrodysplasia ossificans progressiva (FOP) is focused on care, no disease-specific treatment is available.1

Guidelines have been published to address symptomatic relief and the importance of avoiding invasive and traumatic interventions in patients with FOP as they trigger flare-ups and subsequent heterotopic ossification (HO).2,3


  1. Kaplan FS and Glaser DL. Clin Rev in Bone Miner Metabol 2005; 3:243–250.
  2. Pignolo RJ et al. Pediatr Endocrinol Rev. 2013; 10:437–448.
  3. The International Clinical Consortium on FOP The Medical Management of Fibrodysplasia Ossificans Progressiva: Current Treatment Considerations. Proc Intl Clin Council FOP 2019;1:1–111.


Importance of Specialty Care

Care by a healthcare team with experience in treating patients with fibrodysplasia ossificans progressiva (FOP) can help ensure that patients are not put at unnecessary risk of extraskeletal bone formation caused by even minor soft tissue injury.

Learn more about those risks on the FOP Flare-Up page >

clinical features

FOP Research

Information on fibrodysplasia ossificans progressiva (FOP) has grown significantly over the past 10-15 years.

Research is expanding what we know about the natural history of FOP, as well as disease mechanisms.

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Please always consult a healthcare professional if you require healthcare advice or if you have any specific concerns regarding Fibrodysplasia Ossificans Progressiva. The information provided here is not intended to replace professional advice. This website has been developed by Ipsen in collaboration with those living with Fibrodysplasia Ossificans Progressiva and the healthcare professionals who care for them. Ipsen would like to thank everyone for their valuable insights and stories. All names used on this website are not necessarily real names. Visit our website for more information about us, or to contact us directly. Website design and development by Kanga Health Ltd. Website reference NON-US-002031 December 2020